Article Watch, July 2013

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Antibodies to watch in 2013

The transitions of antibody therapeutics to late-stage clinical development, regulatory review and the market are proceeding at a rapid pace in 2013. Since late 2012, two monoclonal antibody (mAb) therapeutics (itolizumab, trastuzumab emtansine) received their first approvals, first marketing applications for three mAbs (vedolizumab, ramucirumab, obinutuzumab) were submitted to regulatory agenc...

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Vet July 2013.indd

Oral canine malignant melanoma is a spontaneous, locally aggressive, and highly metastatic tumour. A full clinical staging is required prior to plan a proper treatment, which will combine an aggressive local treatment with systemic therapy (chemotherapy or immunotherapy). This article aims at guiding the practitioners in the first steps of diagnosis and staging and also at providing data regard...

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Package ‘ Harshlight ’ July 18 , 2013

July 18, 2013 Version 1.32.1 Date 2011-02-09 Title A ‘‘corrective make-up’’ program for microarray chips Author Mayte Suarez-Farinas, Maurizio Pellegrino, Knut M. Wittkowski, Marcelo O. Magnasco Maintainer Maurizio Pellegrino Depends R (>= 2.10) Imports affy, altcdfenvs, Biobase, stats, utils Description The package is used to detect extended, diffuse and compact blemis...

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Package ‘ bridge ’ July 4 , 2013

Description Test for differentially expressed genes with microarray data. This package can be used with both cDNA microarrays or Affymetrix chip. The packge fits a robust Bayesian hierarchical model for testing for differential expression. Outliers are modeled explicitly using a $t$-distribution. The model includes an exchangeable prior for the variances which allow different variances for the ...

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Exam Corner July 2013 - Answers

The FRCS (Tr & Orth) examination has three components: MCQs, Vivas and Clinical Examination. The Vivas are further divided into five sections comprising Basic Science, Adult Pathology, Hands, Children’s Orthopaedics and Trauma. The Clinical Examination section is divided into upperand lower-limb cases. The aim of this section in the Journal is to focus specifically on the trainees preparing for...

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ژورنال

عنوان ژورنال: Journal of Biomolecular Techniques : JBT

سال: 2013

ISSN: 1524-0215,1943-4731

DOI: 10.7171/jbt.13-2402-006